We're tackling some of J Mascis's classic Dinosaur Jr riffs / solo parts here in the song Out There – the opener from 1993's Where You Been album.
Get the tone
For guitar selection I'd recommend a Jazzmaster or Strat as you'll want the tremolo bar for the solo, but you could get away with a Tele too if you're not fussed about the vibrato effect!
Any Big Muff-style fuzz pedal will get you close (J Mascis has a signature Ram's Head fuzz and it's actually no different in tonal spec to the standard Ram's Head version), but he will often use his Zvex Double Rock before the fuzz to somewhat tame the sonics. His tone is pretty raucous but there's still clarity to it and stacking the pedals like this helps in that respect.
Standard tuning but you'll need a capo on the third fret.
Video lesson and technique tips
The rhythm parts are fairly straight forward, but the intro requires some dexterity as you'll be adding melody lines while other notes from the chords ring out, plus some arpeggiation to keep things moving.
Some lovely chord voicings throughout too but the main technique is saved for the solo with generous use of the whammy bar to get some pitch vibrato and also to raise the pitch in a few places, whilst still creating that vibrato effect.
It's broken up rhythmically with some dotted 8th and quarter notes peppered here and there, but I wouldn't be too prescriptive here – approach it with a punk rock approach and have fun!