The next step is to split the open fifth into a chord sequence - in other words, we can use the A1, A2and E3 notes as an approximate guide as to how to distance the notes in the chords that follow. Keep in mind that if the notes in the chords are too close together, then the sound becomes muddy and loses its class.
Deadmau5 splits the bottom note at the start of each bar and again after one and a half beats, apart from on the 4th and 5th bars where there are no new notes. The chords span a minimum of 17 semitones from the bottom note to the top note, and up to a maximum of 31 semitones.
The middle note of each chord changes with the bottom note and there’s an extra step halfway through the last beats of bars 1 and 5. Bars 2 and 6 are more melodic, as pictured. The top note of each chord hangs on the E3 note for most of the progression, which sort of implies the fifth harmony throughout.